How to Farm Uniques from Bosses in Diablo 4 (Season 7)

In Diablo 4, players can target farm Uniques, including Mythic Uniques, by defeating specific Lair Bosses. Below, we will cover which bosses drop which Uniques and how to spawn them. You will also find details on cosmetic rewards and links to dedicated guides for each Lair Boss.

Lair Bosses

Lair Bosses are the best way to farm Uniques efficiently. You can fight them from Torment 1 to 4, with higher difficulties offering better chances for Ancestral Uniques. Keep in mind that Duriel and Andariel have twice the drop rate for Mythic Uniques compared to other Lair Bosses.

Grigoire, The Galvanic Saint

Where: Hall of Penitent in Dry Steppes
Materials: 12xLiving Steel (gathered in Helltides, by opening Tortured Offerings)
Cosmetics: Demonbinder Mount Armor (account bound)

All Classes: Penitent Greaves	Mythic Uniques: Melted Heart of Selig Andariel’s Visage Harlequin Crest Ring of Starless Skies	Tyrael’s Might Heir of Perdition Shroud of False Death Shattered Vow
Barbarian: Twin Strikes Rage of Harrogath Battle Trance The Butcher’s Cleaver Unbroken Chain The Grandfather Doombringer	Druid: Earthbreaker Insatiable Fury Hunter’s Zenith Waxing Gibbous The Butcher’s Cleaver Ahavarion, Spear of Lycander Doombringer	Necromancer: Ebonpiercer Howl from Below Greaves of the Empty Tomb The Butcher’s Cleaver Path of Trag’Oul The Grandfather Doombringer
Rogue: Saboteur’s Signet Word of Hakan Grasp of Shadow Shroud of Khanduras Doombringer	Sorcerer: Flameweaver Staff of Lam Esen Iceheart Brais Axial Conduit Ahavarion, Spear of Lycander Doombringer	Spiritborn: Protection of the Prime Peacemonger’s Signet Ring of the Midnight Sun Loyalty’s Mantle Nesekem, the Herald

Demonbinder Mount Armor:

The Beast in the Ice

Where: Glacial Fissure in Fractured Peaks
Materials: 12x Distilled Fear (gathered in Nightmare Dungeons)
Cosmetics: The Skull Torch and Fell Steed Mount Trophies (account bound)

All Classes: Fists of Fate Tassets of the Dawning Sky Paingorger’s Gauntlets	Mythic Uniques: Melted Heart of Selig Andariel’s Visage Harlequin Crest Ring of Starless Skies	Tyrael’s Might Heir of Perdition Shroud of False Death Shattered Vow
Barbarian: Ancients’ Oath Hellhammer Ring of the Ravenous Mantle of Mountain’s Fury The Grandfather Doombringer	Druid: Storm’s Companion Unsung Ascetic’s Wraps Stone of Vehemen Ahavarion, Spear of Lycander Doombringer	Necromancer: Ring of Mendeln Mutilator Plate The Unmaker Indira’s Memory The Grandfather Doombringer
Rogue: Windforce Eaglehorn Beastfall Boots Doombringer	Sorcerer: Gloves of the Illuminator The Oculus Starfall Coronet Strike of Stormhorn Ahavarion, Spear of Lycander Doombringer	Spiritborn: Harmony of Ebewaka Scorn of the Earth Wound Drinker Nesekem, the Herald

The Skull Torch and Fell Steed Mount Trophies:

Echo of Varshan

Where: Malignant Burrow in Hawezar (near the Tree of Whispers)
Materials: 4x Malignant Heart (gathered by completing Whispers and as random drop in Helltides)
Cosmetics: Flesh-weld Rod Mount Trophy (account bound)

All Classes: Frostburn Mother’s Embrace	Mythic Uniques: Melted Heart of Selig Andariel’s Visage Harlequin Crest Ring of Starless Skies	Tyrael’s Might Heir of Perdition Shroud of False Death Shattered Vow
Barbarian: Fields of Crimson 100,000 Steps Gohr’s Devastating Grips Ring of Red Furor The Grandfather Doombringer	Druid: Mad Wolf’s Glee Vasily’s Prayer Greatstaff of the Crone Airidah’s Inexorable Will Ahavarion, Spear of Lycander Doombringer	Necromancer: Bloodless Scream Deathless Visage Deathspeaker’s Pendant Ring of the Sacrilegious Soul The Grandfather Doombringer
Rogue: Condemnation Eyes in the Dark Skyhunter Writhing Band of Trickery Doombringer	Sorcerer: Staff of Endless Rage Esu’s Heirloom Raiment of the Infinite Tal Rasha’s Iridescent Loop Ahavarion, Spear of Lycander Doombringer	Spiritborn: Craze of the Dead God Ring of the Midday Hunt Ring of Writhing Moon Sunstained War-Crozier Nesekem, the Herald

Flesh-weld Rod Mount Trophy:

Lord Zir

Where: The Darkened Way in Fractured Peaks
Materials: 12x Exquisite Blood (gathered by completing Legion Events or killing World Bosses)
Cosmetics: The Diadem of the Ancient Helm (account bound)

All Classes: Razorplate Temerity Yen’s Blessing	Mythic Uniques: Melted Heart of Selig Andariel’s Visage Harlequin Crest Ring of Starless Skies	Tyrael’s Might Heir of Perdition Shroud of False Death Shattered Vow
Barbarian: Arreat’s Bearing Ramaladni’s Magnum Opus Overkill Ugly Bastard Helm The Grandfather Doombringer	Druid: Wildheart Hunger Fleshrender Mjölnic Ryng Malefic Crescent Ahavarion, Spear of Lycander Doombringer	Necromancer: Cruor’s Embrace Blood Artisan’s Cuirass Lidless Wall Kessime’s Legacy The Grandfather Doombringer
Rogue: Scoundrel’s Kiss Asheara’s Khanjar Pitfighter’s Gull Assassin’s Stride Doombringer	Sorcerer: Fractured Winterglass Esadora’s Overflowing Cameo Sidhe Bindings Okun’s Catalyst Ahavarion, Spear of Lycander Doombringer	Spiritborn: Wushe Nak Pa Band of First Breath Jacinth Shell Nesekem, the Herald

The Diadem of the Ancient Helm:

Duriel and Andariel

Duriel:

Where: Gaping Crevasse in Kehjistan
Materials: 2x Mucus-Slick Egg (drops from Grigoire) and 2x Shard of Agony (drops from Varshan)
Cosmetics: Smouldering Brimstone Mount (account bound)

Andariel:

Where: Hanged Man’s Hall in Kehjistan
Materials: 2x Sandscorched Shackles (drops from The Beast in the Ice) and 2x Pincushioned Doll (drops from Lord Zir)
Cosmetics: Smouldering Brimstone Mount (account bound)

For a more detailed page on how to farm Mythic Uniques, check out our dedicated guide:

All Classes: Azurewrath Godslayer Crown Flickerstep Tibault’s Will X’Fal’s Corroded Signet Soulbrand Banished Lord’s Talisman	Mythic Uniques: Melted Heart of Selig Andariel’s Visage Harlequin Crest Ring of Starless Skies	Tyrael’s Might Heir of Perdition Shroud of False Death Shattered Vow
Barbarian: Tuskhelm of Joritz the Mighty The Grandfather Doombringer	Druid: Tempest Roar Dolmen Stone Ahavarion, Spear of Lycander Doombringer	Necromancer: Black River Blood Moon Breeches The Grandfather Doombringer
Rogue: Cowl of the Nameless Scoundrel’s Leathers Doombringer	Sorcerer: Flamescar Blue Rose Ahavarion, Spear of Lycander Doombringer	Spiritborn: Rod of Kepeleke Sepazontec Nesekem, the Herald

Smouldering Brimstone Mount:

Infernal Hordes

Infernal Hordes also offer you access to certain Uniques. These Uniques can also be gathered from Whisper caches.

All Classes: Endurant Faith Rakanoth’s Wake	Shard of Verathiel Crown of Lucion Locran’s Talisman
Barbarian: The Third Blade	Druid: The Basilisk	Necromancer: The Mortacrux
Rogue: The Umbracrux	Sorcerer: Vox Omnium

Good luck farming your Uniques! Before taking on Lair Bosses, make sure to check which Uniques are best for your build so you can target the right bosses.