Since his introduction in Season of Blood, we were able to fight Lord Zir as his Level 80 version in WT4. Now with Vessel of Hatred and Season 6, we are able to adjust the challenge of fighting Lord Zir just by changing the difficulty that we are playing on. The higher the difficulty, the more loot that will drop. As with other endgame bosses, Lord Zir has a special pool of uniques that he can drop.
How to Summon Lord Zir
To Summon Lord Zir you must acquire 12 
Exquisite Blood from Legion Events, World Bosses, and random drops from elites and treasure goblins during Helltides.
You then take those to The Darkened Way east of Kyovashad, and once you go inside look on your map for the Ancient’s Seat. Fight your way through, and then use the materials at the altar to summon Lord Zir.
Preparations
- Get your Shadow Resistance as high as possible, including increasing your Max Shadow Resist through items like
Elixir of Shadow Resistance II. - Play a build that you are comfortable with and that has shown to have enough damage and survivability to take on bosses (check out our Tier list here for suggestions).
Boss Mechanics
Lord Zir has a few abilities that are Shadow based so make sure that your Shadow resistance is capped, and you use an Elixir of Shadow Resistance II.
Stagger Bar: Like most bosses in Diablo 4, Lord Zir has a stagger bar. Filling this bar will stun her, allowing you to deal damage without worrying about his attacks for a few seconds.
During the fight, in addition to his default attacks, Lord Zir has a few mechanics to look out for:
- Blood Puddles: Red Puddles on the ground, make sure to avoid them, or you will take heavy damage.
- When he raises both arms for his frontal attack, run or evade to place yourself behind his back.
- Blood Globes: About halfway through the fight, he will spawn Blood Globes all over the room, and you need to avoid them.
- Towards the end of the fight (around 30% HP left) he will fly up into the air, then land and spawn a void zone that will spawn little flying blood orbs.
- Adds: Throughout the fight, he will summon adds that you may remember from the Season of Blood
- Elite Bloodseeker: Starting about 25% into the fight or around 75% HP left Lord Zir will start to summon Elite Bloodseekers and random intervals.
Drops
All Classes:
Razorplate
Temerity
Yen’s Blessing- The Diadem of the Ancient Helm
Sorcerer:
Druid:
Barbarian:
Necromancer:
Rogue:
Spiritborn:
