In Diablo 4, Mythic Uniques are designed to be game-changers, items so powerful they define entire builds. But not all of them deliver on that promise! Rob2628 has released a comprehensive video that ranks every Mythic Unique in the game, breaking them into clear tiers for S to F.
F-Tier: The Forgotten Ones
The following Mythic Uniques rarely see any use. They require serious rework and improvements to become viable:
C-Tier: Niche, But Playable
While not widely used, these Mythic Uniques have niche usage, mostly in Hardcore or during early progression until you find better options.
B-Tier: Solid Overall
These Mythic Uniques find value in specific setups, particularly for Overpower builds and in Hardcore.
S-Tier: The Best of the Best
The following Mythic Uniques are the strongest in the game and considered mandatory for many builds. They are nearly always used in top builds.